Clinical presentation and staging of newly diagnosed intraocular retinoblastoma according to international classification of retinoblastoma

To report the clinical presentation and stage of the disease in newly diagnosed retinoblastoma cases at Al-Shifa Trust Eye Hospital Rawalpindi according to International Classification of Retinoblastoma. A hospital based prospective descriptive study. Clinical data of presentation and staging of cases diagnosed with primary retinoblastoma from January 2009 to June 2011 was collected. All patients underwent an examination under anaesthesia including fundus examination by indirect ophthalmoscopy with 360 degrees indentation, ultrasound and RetCam photographs to document the location and size of the tumours, the presence and extent of vitreous and subretinal seedings and subretinal fluid. An oncologist performed the metastatic workup. All the eyes were then classified according to the Reese-Ellsworth classification and International classification of retinoblastoma [IIRC]. Treatment methods included chemoreduction, focal therapy [transpupillary thermotherapy and cryotherapy], enucleation and exenteration in rare cases with extra ocular extension. 72 eyes of 51 patients with primary retinoblastoma were diagnosed during this period. Thirty patients [58.8%] had unilateral retinoblastoma and 21 patients [41.2%] had bilateral retinoblastoma. Thirty four [66.6%] patients presented with leukocoria. The disease in 32 [62.74%] patients was classified in group E. Majority of the patients presented with advanced disease manifesting as leukocoria and were staged in group E

visual outcomes and complications of intraocular lens implantation in children aged 1 year or less

To present the visual outcomes and complications of intraocular lens [IOL] implantation in children aged 1 year or less. A total of 30 consecutive eyes of 19 children undergoing cataract removal combined with IOL implantation at less than I year of age were evaluated. SRK-T formula was used to calculate the IOL power and emmetropic power was under corrected by 20%. After aspiration of the lens matter and posterior capsule polishing, acrylic hydrophilic foldable or PMMA rigid IOL was implanted by a paediatric Ophthalmologist. Visual acuity, refractive status and postoperative complications were recorded throughout the 12 months of follow up. Data was analyzed using SPSS version 13.0, Out of 19 children, 8 [42.1%] had unilateral cataract [8 eyes], and 11 [57.9%] had bilateral cataracts [22 eyes]. Mean age at the time of surgery was 8.7 [ +/- 2.5] months. Foldable IOL implantation in capsular bag was achieved in 17 [56.7%] eyes while sulcus fixation of IOL was done in 13 [43.3%] eyes. Mean post-operative refraction was +5.97 [ +/- 2.60] DS. Postoperative fibrinous reaction was seen in 4 [13.3%] eyes, visually significant PC0 requiring surgical posterior capsulotomy developed in 2 [6.66%] eyes while 24 eyes [80%] retained a clear visual axis during the follow up period. Lens matter aspiration combined with IOL implantation in children less than 1year of age resulted in better visual outcomes with acceptable risk to benefit ratio. 101, power calculations and refractive outcomes were predicted satisfactorily using SRK-T formula with 20% under correction